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peptides

  • Nocistatin (bovine)
    Nocistatin (bovine)
    • Cat. No.:
    • B013098
    • CAS No.:
    • Molecular Formula:
    • C82H135N21O32
    • Molecular Weight:
    • 1927.1 g/mol
    Description
    An endogenous peptide derived from the same precursor as nociceptin, which is able to block nociceptin-induced allodynia and hyperalgesia and may play an opposing role in pain transmission. Shown to reverse noci...
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  • alpha-D-Mannose
    alpha-D-Mannose
    • Cat. No.:
    • B013086
    • CAS No.:
    • 135317-04-3
    • Molecular Formula:
    • C6H12O6
    • Molecular Weight:
    • 180.16 g/mol
    Description
    It is a member of a family of snake three-finger toxin derived from the venom of African mamba snake Dendroaspis angusticeps 86-amino acid peptide with 4 disulfide bridges , derived fr...
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  • N-Acetyl-leu-met-asp-lys-glu-ala-val-tyr-phe-ala-his-leu-asp-ile-ile-trp
    N-Acetyl-leu-met-asp-lys-glu-ala-val-tyr-phe-ala-his-le...
    • Cat. No.:
    • B013114
    • CAS No.:
    • 143113-45-5
    • Molecular Formula:
    • C96H140N20O25S
    • Molecular Weight:
    • 1934.3 g/mol
    Description
    Highly potent and selective ETB endothelin receptor agonist (Ki values are 0.18 and 970 nM at human ETB and ETA receptors respectively).
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  • Epitalon
    Epitalon
    • Cat. No.:
    • B013367
    • CAS No.:
    • 307297-39-8
    • Molecular Formula:
    • C14H22N4O9
    • Molecular Weight:
    • 390.35 g/mol
    Description

    Epitalon, also known as Epithalon or Epithalamin, is a synthetic tetrapeptide composed of four amino acids: alanine, glutamic acid, aspartic acid, and glycine. This compound has garnered significant attention in the fields of aging and longevity research due to its purported ability to activate the enzyme telomerase, which plays a crucial role in maintaining telomere length and cellular health.

    Epitalon is classified as a telomerase activator, which means it can potentially extend the lifespan of cells by promoting the elongation of telomeres—protective caps at the ends of chromosomes that shorten with each cell division. Shortened telomeres are associated with aging and age-related diseases. Research indicates that Epitalon may reduce oxidative stress and improve cellular function, thereby contributing to longevity and overall health.

    Brief History and Development of Epitalon

    The origins of Epitalon trace back to the 1980s in Russia, where it was first developed from extracts of the pineal gland. Researchers at the St. Petersburg Institute of Bioregulation and Gerontology, particularly Vladimir Khavinson, conducted extensive studies on its effects on aging. Initial animal studies demonstrated that Epitalon could significantly prolong lifespan in various species, including fruit flies and rodents. For instance:

    In fruit flies, Epitalon reduced mortality rates by 52%.

    In mice prone to heart disease and cancer, it extended lifespan by up to 27% compared to controls.

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  • Desmopressin (Acetate)
    Desmopressin (Acetate)
    • Cat. No.:
    • B013380
    • CAS No.:
    • 62288-83-9
    • Molecular Formula:
    • C48H68N14O14S2
    • Molecular Weight:
    • 1129.3 g/mol
    Description
    Desmopressin Acetate is an analogue of the hormone vasopressin with antidiuretic and antihemorrhagic properties. Desmopressin acetate has selective affinity for the V2 receptor and acts on the distal kidney tubu...
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  • Dadle
    Dadle
    • Cat. No.:
    • B013295
    • CAS No.:
    • 63631-40-3
    • Molecular Formula:
    • C29H39N5O7
    • Molecular Weight:
    • 569.6 g/mol
    Description
    A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.
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  • Boc-Met-Leu-Phe-OH
    Boc-Met-Leu-Phe-OH
    • Cat. No.:
    • B013294
    • CAS No.:
    • 67247-12-5
    • Molecular Formula:
    • C25H39N3O6S
    • Molecular Weight:
    • 509.7 g/mol
    Description
    Antagonist of formyl peptide receptor 1 (FPR1). Reduces superoxide production induced by fMLF with an EC50 of 0.63 μM. Almost completely blocks fMLF-stimulated primary granule exocytosis....
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  • Seglitide
    Seglitide
    • Cat. No.:
    • B013172
    • CAS No.:
    • 81377-02-8
    • Molecular Formula:
    • C44H56N8O7
    • Molecular Weight:
    • 809.0 g/mol
    Description
    Peptide agonist for sst2 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: > 1000 (sst1), 0.2 - 1.5 (sst2), 27 - 36 (sst3), > 127 (sst4), and 0.06 - 23 (sst5)....
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  • Obestatin
    Obestatin
    • Cat. No.:
    • B013227
    • CAS No.:
    • 869705-22-6
    • Molecular Formula:
    • C114H174N34O31
    • Molecular Weight:
    • 2516.8 g/mol
    Description
    A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimula...
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  • alpha-CGRP (human)
    alpha-CGRP (human)
    • Cat. No.:
    • B013247
    • CAS No.:
    • 90954-53-3
    • Molecular Formula:
    • C163H267N51O49S2
    • Molecular Weight:
    • 3791.3 g/mol
    Description
    Endogenous calcitonin gene related peptide agonist. Vasorelaxant, releases nitric oxide and stimulates guanylate cyclase in vivo. Active in vivo and in vitro. Rat isoform also available.
    Endogenous calcitonin...
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